Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 (PubMed:2303490, PubMed:31442408, PubMed:32325220, PubMed:6334084). Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (PubMed:32325220). Also possesses beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem (PubMed:32325220, PubMed:6334084)
Homodimer; disulfide-linked
Expressed in lung and kidneys
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Genes with an experimentally identified or computationally predicted synthetic-lethal relationship to DPEP1, aggregated across our SSL data sources. Click any partner node to view that gene’s page.
Nodes and edges are coloured by the SSL data source. Partners appearing in more than one source are shown in grey.
Total Trials Found: 2
| NCT ID | Condition | Brief Title | Phase | Status |
|---|---|---|---|---|
| NCT00810225 | Gulf War Illness, Persian Gulf War Syndrome | Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans | N/A | COMPLETED |