The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover
Interacts with GPRASP2 (PubMed:15086532). Interacts with TMEM147 (PubMed:21056967)
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Genes with an experimentally identified or computationally predicted synthetic-lethal relationship to CHRM1, aggregated across our SSL data sources. Click any partner node to view that gene’s page.
Nodes and edges are coloured by the SSL data source. Partners appearing in more than one source are shown in grey.
No clinical trials information available.